The Antioxidant Effects of Kratom

June 24, 2017 Articles, Kratom Research


Ever since the FDA put pressure on the DEA to ban kratom and the DEA falesly claimed that it was a “synthetic substance,” people have been questioning its value as a natural remedy. There is plenty of literature out there pointing to the usefulness of the M. speciosa (kratom) plant, but not everyone knows about kratom’s antioxidants.

Well, it turns out there have been many scientific probes into the chemical make-up of Mitragyna speciosa, its active alkaloids and its bioavailability.

In today’s post, we’ll break down exactly what kratom contains and what the experts have to say about kratom and its potential benefits.


Antioxidants are important because they can eliminate potentially damaging oxidizing agents in the human body. And as one user claimed in a Longecity post, “Kratom contains over 20 times the number of antioxidants of green tea.”

In a study published by US National Library of Medicine National Institutes of Health, kratom’s antioxidants and potential anticancer properties were investigated. The results were demonstrative with the scientists concluding that kratom’s analogues could be promising as antioxidant, anticancer and chemopreventative compounds.

Kratom has even landed on a list of the top 12 cancer prevention strategies and people have started to share their anticancer kratom experiences in YouTube videos like this one.


Naturally, all the studies haven’t resulted in such postive findings. One extended study conducted on animals suggested that acute mitragynine exposure could cause impaired passive avoidance learning, memory consolidation and retrieval.

Those who conducted the study believe that this degeneration of memory and impairment of learning skills could be the consequence of mitragynine disrupting cortical oscillatory activity in the brain, such as the suppression of delta and theta rhythms.

The main takeaway of the study supported the hypothesis that kratom has potential for addiction as the changes in memory and learning skills were linked to chronic mitragynine use. This particular element of the study does not bode well for daily kratom users as it shows that kratom can be every bit as addictive as other drugs that affect opiod receptors.


While many fake news outlets have spread lies about kratom deaths and kratom overdoses, experts have weighed in on the subject and they’ve got mostly positive things to say about M. speciosa and the active kratom alkaloids.

Southern California-based Dr. Phil Schoenwetter, MD even wrote about the wonders that kratom may have on migraine headaches, writing, “My first encounter with Kratom was stunning and unexpected. Janet, my wife of 35 years, suffers from migraines and last year had a breakthrough episode that normally would require strong pharmaceutical treatment.

“While fueling our SUV at a Chevron station in Nevada, Janet went to the food mart and noted a lady requesting her daily eight capsule packet of Kratom. The kind lady said it helped with her midlife aches and pains and no other adverse side effects.

“Janet purchased the same packet and took one capsule. Although a licensed physician in several states since 1978, I had not even encountered the word ‘Kratom.’ Some 60 miles down the road Janet announced she was OK, pain free, clear of thought, (not ‘loaded’ as with morphine) and ready to take the wheel, which she did flawlessly for some 165 miles.

Dr. Schoenwetter goes on to say that this experience served as a clarion call to delve deeper into the realm of natural agents and to better understand the mechanisms of action so as to implement them as part of his family medical practice.

He also points out that there are infrequent adverse reactions from kratom use, writing that they are minimal, transient and most often limited to light heartburn. He adds, “Kratom already is a ‘must have’ adjunct to numerous long term conditions and its role in my practice already exceeds the ‘usual and customary’ uses that one normally will find referenced in literature found on the internet.”

And he’s not the only one! Dr. Ray Estevez, a psychopharmacologist out of Tampa says, “I am well versed in both ‘good’ drugs that help people on a daily basis, and ‘bad’ drugs that are epidemically abused and create a tremendous burden on society.

“Kratom is [a natural herbal supplement] and not one of these ‘bad’ drugs (I have yet to admit anyone for kratom-addiction) and efforts to ban it are misguided and wasteful. Grieving parents, well intentioned policy makers, and opportunist politicians often seize on opportunities to assign blame and then offer a ‘quick fix.’

“The proposal of an absolute ban of Kratom perfectly illustrates what can happen when hype trumps science, as this plant has been benefiting millions of people for decades of time. I have been troubled by an increase in news reports and misinformation that has been disseminated about the ‘dangerous’ and ‘addictive drug’ Kratom.

“Even worse is the subsequent careless and knee-jerk response by many legislators and policy makers to ban Kratom. I believe much of the negative publicity surrounding Kratom to be the result of being incorrectly lumped in with synthetically derived mind-altering substances such as ‘spice” and bath-salts, substances that deserve their reputations for being dangerous and harmful.”

Other medical experts who have advocated for kratom use include perennial Dr. Oz Show favorite Dr. Josh Axe who extols the virtues of kratom in an article entitled “Kratom: Harmful Banned Substance or Safe Drug Addiction Treatment?

In it, he discusses its pain relief and energy-boosting benefits as well as the ways in which it has helped drug addicts kick nasty addictions to illicit substances and dangerous prescription pain killers.


So there you have it! Kratom may be good for so many people for so many reasons and now we know just a bit more than we did before. When using kratom for aromatherapy, always use responsibly. Use only the recommended dose and avoid chronic use. Be safe, be smart and be well.

Bob Freville
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